Mate Ravasz

Postdoctoral research associate

Mate Ravasz

Research interests

Our lab is primarily interested in elucidating the role of protein tyrosine phosphatase nonreceptor type 22 (Ptpn22) in the immune response. Within this framework I focus on finding and characterizing the binding partners of Ptpn22 in murine T cells and mapping early signalling events upon T cell receptor (TCR) stimulation. I am most interested in applying high-throughput approaches and bioinformatics to better understand these networks. With my results I hope to shed more light not only on the function of Ptpn22 upon TCR stimulation, but also on its role in the development of autoimmune diseases like rheumatoid arthritis and diabetes.

Experimental techniques

  • Ex-vivo T cell culture and T cell activation assays
  • Flow cytometry
  • Immunoprecipitation and affinity purification of proteins
  • Western blotting
  • Mass spectrometry
  • Scripting in Python and R

Additional activities

  • Coordinating our group's education and public outreach activities
  • Supervising honour students
  • Organizing the institute's weekly seminar series
  • Demonstrating at the coding for immunologists course
  • Being the designated computer repair guy in the lab

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